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USP38 Standard 99% API Powder Donepezil Hydrochloride/Donepezil HCl/CAS 120011-70-3

USP38 Standard 99% API Powder Donepezil Hydrochloride/Donepezil HCl/CAS 120011-70-3

Donepezil hydrochloride is a long-acting Alzheimer's disease (AD) in the symptomatic treatment drugs. FZBIOTECH,as a manufacturer of monomer, has been devoting to supplying the best quality Benzothiophene powder to all over the world with best price. Chat Now
Description

Basic Information of Donepezil Hydrochloride

Product Name: Donepezil HCl, Donepezil Hydrochloride

MF: C24H30ClNO3

MW.: 415.9529

Purity: >99%

Appearance: white powder

CAS: 120011-70-3

Structural Formula:

120011-70-3.png

Introduction of Donepezil Hydrochloride

Donepezil Hydrochloride is a noncompetitive acetylcholinesterase inhibitor (IC50 = 11.6 nM. It is known that Donepezil Hydrochloride is a useful tool in the study of Alzheimer's disease. Studies indicate that Donepezil Hydrochloride protects thebrain against diisopropylfluorophosphate-induced effects. Studies indicate that Donepezil Hydrochloride selectively inhibits acetylcholinesterase, whereas it has little effect on butyrylcholinesterase. Alternate studies suggest that Donepezil Hydrochloride increases the concentration of extracellular acetylcholine.


Benefits of Donepezil Hydrochloride

Donepezil hydrochloride is a long-acting Alzheimer's disease (AD) in the symptomatic treatment drugs. AD is a kind of memory loss as the main performance, accompanied by other cognitive impairment of acquired intelligence decline. Nearly 30 years of research show: AD progressive degeneration of cholinergic neurons is memory loss, disorientation, personality changes and behavioral reasons, such cholinergic theory has been confirmed by histological study. Donepezil hydrochloride is a second-generation cholinesterase (ChE) inhibitor, its therapeutic effect is reversibly inhibiting acid hydrolysis of acetylcholine acetylcholinesterase (AchE) caused by increased content of acetylcholine receptor sites. Donepezil may have other mechanisms, including the disposal of the direct effect of the peptide, neurotransmitter receptors, or Ca2 + channels.


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Xi'an Fengzu Biological Technology Co.,Ltd
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