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USP Standard Bupivacaine Powder/2180-92-9

USP Standard Bupivacaine Powder/2180-92-9

Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area.FZBIOTECH,as a manufacturer of monomer, has been devoting to supplying the best quality Bupivacaine powder to all over the world with best price. For long term cooperation, free sample is available. Chat Now
Description

Basic Information of Bupivacaine
Other Name:Bupivacaine Hydrochloride
Molecular Formula:C18H28N2O
Molecular Weigh:288.428
Appearance:White crystal powder
Synonyms:1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
Boiling Point:436ºC at 760 mmHg
Density:1.014g/cm3
Purity:99%
CAS:2180-92-9
Structural Formula:
lidocaine prilocaine.png
Introduction of Bupivacaine
It is used by injecting it into the area, around a nerve that supplies the area, or into the spinal canal's epidural space. It is available mixed with a small amount of epinephrine to make it last longer. It typically begins working within 15 minutes and lasts for 2 to 8 hours.
Possible side effects include sleepiness, muscle twitching, ringing in the ears, changes in vision, low blood pressure, and an irregular heart rate. Concerns exist that injecting it into a joint can cause problems with the cartilage. Concentrated bupivacaine is not recommended for epidural freezing. Epidural freezing may also increase the length of labor. It is a local anaesthetic of the amide group.

Adverse effects of Bupivacaine
Compared to other local anaesthetics, bupivacaine is markedly cardiotoxic. However, adverse drug reactions (ADRs) are rare when it is administered correctly. Most ADRs are caused by accelerated absorption from the injection site, unintentional intravascular injection, or slow metabolic degradation. However, allergic reactions can rarely occur.
Clinically significant adverse events result from systemic absorption of bupivacaine and primarily involve the central nervous system (CNS) and cardiovascular system. CNS effects typically occur at lower blood plasma concentrations. Initially, cortical inhibitory pathways are selectively inhibited, causing symptoms of neuronal excitation. At higher plasma concentrations, both inhibitory and excitatory pathways are inhibited, causing CNS depression and potentially coma. Higher plasma concentrations also lead to cardiovascular effects, though cardiovascular collapse may also occur with low concentrations. Adverse CNS effects may indicate impending cardiotoxicity and should be carefully monitored.

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Xi'an Fengzu Biological Technology Co.,Ltd
Manufacturer Add: Industrial Park in Wugong County, Xianyang City,Shaanxi Province, China.
Office Add: 21F, Tangfengguoji,No.18 Fenghuinanlu, Xi'an City, Shaanxi Province, China.
Office Tel: 86-029-89561932/86-135-7248-9476             Office Fax: 86-029-8918-9705
Email: sales@fengzusw.com                                            Skype: fengzusw