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What is Dehydroepiandrosterone (DHEA) Uses Dosage and efficacy

Dehydroepiandrosterone (DHEA), also known as androstenolone, is an endogenous steroid hormone. It is the most abundant circulating steroid hormone in humans, in whom it is produced in the adrenal glands, the gonads, and the brain, where it functions predominantly as a metabolic intermediate in the biosynthesis of the androgen and estrogen sex steroids.

Dehydroepiandrosterone (DHEA) is a hormone produced by the body's adrenal glands. The body uses DHEA to make androgens and estrogens, the male and female sex hormones. DHEA levels peak at about age 25, then go down steadily as you get older. By the time people are 70 to 80 years old, their DHEA levels are only 10 to 20% those in young adults.

Because levels of DHEA decline with age, researchers have wondered if DHEA could work as an anti-aging treatment. In older people, lower than normal levels of DHEA have been associated with osteoporosis, heart disease, memory loss, and breast cancer. But there's no proof that low levels of DHEA cause these conditions, or that taking DHEA can help prevent them. Plus DHEA supplements vary widely in quality. Many products tested don't have the amount of DHEA in them that the label says they do.

Uses of Dehydroepiandrosterone (DHEA)

Adequately powered, long-term clinical trials are lacking to support a place in therapy for dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) supplementation (henceforth, jointly referred to as DHEA/S). Reviews of clinical trials found no convincing evidence to support a place in therapy for postmenopausal symptoms in women, in improving cognitive function or physical strength in elderly patients, in hyperlipidemia or insulin resistance, or in schizophrenia or cancer. Some evidence exists to support the use of DHEA/S supplementation in women with diminished ovarian reserves, in subpopulations of elderly women with osteoporosis, and in mild systemic lupus erythematosus.

Dosage of Dehydroepiandrosterone (DHEA)

DHEA is available as oral preparations, intraoral sprays, and transdermal creams and gels.

Orally administered DHEA has a low bioavailability (less than 10%), and intravenous DHEA is subject to rapid hepatic clearance. Transdermal and subcutaneous routes offer greater bioavailability. 1Oral DHEA is converted into inactive DHEAS, which can then act as a reservoir for the body to utilize. DHEA 200 mg/day given to healthy men for 1 week resulted in a DHEA level of 1 mcg/dL and a DHEAS level of 400 mcg/dL. 

Effects in HIV-Infected Patients

In a recent open-label trial evaluating the effect of DHEA on depressed mood and fatigue, 45 HIV-positive patients (39 men and 6 women) received oral DHEA doses of 200-500 mg/day for eight weeks. Of the 32 patients who completed the trial, 23 (72%) had an improvement in mood and 26 (81%) had a reduction in fatigue. There was a significant increase in body cell mass and libido but no effect on CD4+ lymphocyte counts or testosterone levels in men. The positive effects on mood, fatigue, and body cell mass continued for an additional four weeks in a subsequent double-blind phase of the study. 

Where to buy Dehydroepiandrosterone (DHEA)?

You may have deep understanding of Dehydroepiandrosterone (DHEA) . Xi'an Fengzu Biological Techology Co.,Ltd., as a China professional supplier of monomer, has been devoting to providing various monomer with favorable price. You can send E-mail to sales@fengzusw.com directly for a competitive price and professional knowledge. For long time cooperation, free samples is available. We're looking forward your inquiry.

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