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The Benefits of D Mannose-FZBIOTECH

D-Mannose is a natural occurring simple sugar that appears to be a safe, practical alternative for the treatment of urinary tract infections (UTI’s). D-Mannose is absorbed eight times slower than glucose, and when ingested, is not converted to glycogen or stored in the liver, but rather goes directly to the blood stream from the upper GI tract. Hence, D-Mannose is mostly filtered through the kidneys and routed to the bladder lining is comprised of polysaccharide molecules. Finger-like projections on the cell surface of E. coli bacteria adhere to these molecules, initiating an infection. In the presence of D-Mannose, E. coli preferentially attach to D-Mannose molecules forming a complex which is expelled with the next voiding.

The major health benefits of this sugar are to treat urinary tract infection, improve bladder health and boost digestive health.


Cranberry juice is famous for its ability to help treat a nasty infection of the urinary tract. This ability is derived from its active compound – D-mannose. There is plenty of research that shows D-mannose can help treat a UTI.

In a study published in 2014, 308 women suffering from frequent UTIs were divided into 3 groups. The first group was treated with a 2 gram dose of D-mannose each day for 6 months. The other groups were either given a prescription drug (nitrofurantoin) used for UTIs or given no treatment at all.

After the 6 month trial had finished, the researchers found that only 14% of the women given D-mannose had suffered a recurrence of her UTI compared with 20% in the prescription drug group. 60% of those who received no treatment suffered over experienced a recurrence of her infection. 

The researchers concluded that D-mannose had a significant effect in reducing the risk of a recurrent UTI similar to that of the prescription medication. In addition they found that the risk of side effects was significantly reduced compared with the group who took nitrofurantoin.


As well as its proven ability to treat urinary tract infections, research has also revealed that D-mannose can help treat other bladder conditions and improve bladder health overall.

Several studies have looked at the effects of D-mannose on the ability of the E. Coli bacteria to adhere to the human urinary tract cell. In one study, researchers found that when levels of D-mannose decreased, so the ability of the E.coli bacteria to adhere onto the cells was increased. 

Another similar study was done around the same time to analyze its effects on rats producing excessive urine related to E. coli. The research found that the levels of E. coli bacteria were considerably lower when rats were treated with supplementary D-mannose


Studies have also revealed that D-mannose has the potential to improve digestive health and protect against various digestive complaints including duodenal ulcers, irritable bowel syndrome and potentially even cancer.

One recent study which was published in 2014 set out to analyze the relationship between glyconutrients and illnesses of patients suffering duodenal ulcers and gastric cancer. What the researchers found was very interesting.

Those patients suffering with gastric cancer were also likely to have reduced levels of mannose glycans. The researchers found similar results in people suffering from duodenal ulcers. 

There is also plenty of evidence from in vitro and animal studies demonstrating that D-mannose may help protect the body against the adverse effect of lectins. These are a type of protein found commonly in certain legumes, seeds, grains and beans. Lectins are also present in some vegetables and fruits.

Lectins are a big part of the Western diet and do not degrade in your stomach acid. This makes them extremely resistant and difficult to digest. Lectins are carried by microbes which use them to attach to host cells.

Studies done in vitro and on animals have revealed that D-mannose functions as a type of decoy molecule. It is able to bind to various irritants and allergenic compounds which would ordinarily bind to the mannose sugar on the cells. This protects the body from reactions related to lectin such as irritable bowel syndrome, other inflammatory bowel complaints and possibly colon cancer. 

Where to buy D-mannose powder?

You may have deep understanding of D-mannose. Xi'an Fengzu Biological Techology Co.,Ltd., as a China professional supplier of D-mannose powder, has been devoting to providing various monomer with favorable price. You can send E-mail to sales@fengzusw.com directly for a competitive price and professional knowledge. For long time cooperation, free samples is available. We're looking forward your inquiry.

Xi'an Fengzu Biological Technology Co.,Ltd
Manufacturer Add: Industrial Park in Wugong County, Xianyang City,Shaanxi Province, China.
Office Add: 21F, Tangfengguoji,No.18 Fenghuinanlu, Xi'an City, Shaanxi Province, China.
Office Tel: 86-029-89561932/86-135-7248-9476             Office Fax: 86-029-8918-9705
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