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The Benefit of Ginsenoside

Ginseng occupies a prominent position in the list of best-selling natural products in the world. Compared to the long history of use and widespread research on Asian ginseng, the study of American ginseng is relatively limited. In the past decade, some promising advances have been achieved in understanding the chemistry, pharmacology and structure-function relationship of American ginseng. To date, there is no systematic review of American ginseng. In this review, we present the different structures of the ginseng root extract ginsenosides in American ginseng, including naturally occurring compounds and those resulting from steaming or biotransformation. Preclinical and clinical studies published in the past decade will also be discussed. We highlight the chemical and pharmacological diversity and potential structural-activity relationship of ginsenosides. Our hope is that this article is a useful reference to chemists and biologists researching American ginseng, and will open the door to novel agents in drug discovery.


Found exclusively in the ginseng, ginsenosides are among the most sought-after steroidal saponins in nature. Ginsenosides are thought to improve resistance to stress and enhance homeostasis. They are as well purported to be of a great effect on workers, fostering their mental and physical capabilities. Recently, studies reported a close link between the uses of ginsenoside rh2 and man’s fertility. Other studies –still not confirmed- say that ginsenosides extracted from Asian ginseng can help treat cancer, heart disease, as well as several respiratory problems.


Where to buy ginsenoside?
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