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Superoxide Dismutase

Superoxide Dismutase

Superoxide Dismutase (SOD, EC 1.15.1.1) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O2) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2).FZBIOTECH,as a manufacturer of Superoxide Dismutase, has been devoting to supplying the best quality Superoxide Dismutase to all over the world with best price. For long term cooperation, free sample is available.Chat Now
Description

Basic Information of Superoxide Dismutase
Product Name: Superoxide Dismutase
Other Name: SOD
Appearance: White or light blue crystalline powder
Enzyme activity: 1000U/mg-8000U/mg
EC number: 1.15.1.1
Protein content: 85%
Cas No.: 9054-89-1
EINECS: 232-943-0
Supplier: FZBIOTECH

Brief Introduction of Superoxide Dismutase
Superoxide Dismutase (SOD, EC 1.15.1.1) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O2) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive (O2).

Application of Superoxide Dismutase
Activity
Superoxide dismutase (SOD) has powerful antinflammatory activity. For example, SOD is a highly effective experimental treatment of chronic inflammation in colitis. Treatment with SOD decreases reactive oxygen species generation and oxidative stress and, thus, inhibits endothelial activation and indicate that modulation of factors that govern adhesion molecule expression and leukocyte-endothelial interactions. Therefore, such antioxidants may be important new therapies for the treatment of inflammatory bowel disease.
Cosmetic uses
Superoxide dismutase (SOD) may reduce free radical damage to skin—for example, to reduce fibrosis following radiation for breast cancer. Studies of this kind must be regarded as tentative, however, as there were not adequate controls in the study including a lack of randomization, double-blinding, or placebo. Superoxide dismutase is known to reverse fibrosis, perhaps through reversion of myofibroblasts back to fibroblasts.
Commercial sources
Superoxide dismutase (SOD) is commercially obtained from bovine liver, horseradish, cantaloupe and by fermenting certain bacteria, though it is found in most living forms at diverse concentrations. For therapeutic purpose, SOD is usually injected locally. There is no evidence that ingestion of unprotected SOD or SOD-rich foods can have any physiological effects: as all ingested SOD is broken down into amino acids before being absorbed. However, ingestion of SOD bound to wheat proteins could improve its therapeutic activity, at least in theory.


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Xi'an Fengzu Biological Technology Co.,Ltd
Manufacturer Add: Industrial Park in Wugong County, Xianyang City,Shaanxi Province, China.
Office Add: 21F, Tangfengguoji,No.18 Fenghuinanlu, Xi'an City, Shaanxi Province, China.
Office Tel: 86-029-89561932/86-135-7248-9476             Office Fax: 86-029-8918-9705
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