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China Manufacturers Supply 99% Irinotecan Hydrochloride,Irinotecan Powder

China Manufacturers Supply 99% Irinotecan Hydrochloride,Irinotecan Powder

Irinotecan, sold under the brand name Camptosar among others, is a medication used to treat colon cancer and small cell lung cancer.FZBIOTECH,as a manufacturer of monomer, has been devoting to supplying the best quality Irinotecan powder to all over the world with best price. For long term cooperation, free sample is available. Chat Now
Description

Basic Information of Irinotecan
Other Name:Camptosar,Irinotecan hcl
Molecular Formula: C33H38N4O6
Molecular Mass:586.678
Appearance: Creamish to pale yellow powder
Test Method: HPLC
Content: 99%
CAS:97682-44-5
Structural Formula:
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Introduction of Irinotecan
Irinotecan is a semi-synthetic derivatives of camptothecin which can be specifically combined with the topoisomerase I. Topoisomerase I induced reversible single-strand breaks, so that double-stranded structure of DNA unwinded. Irinotecan and its active metabolite SN-38 with topoisomerase I-DNA complex binding, thereby preventing the fractured single-stranded nucleic acid to be connected. Existing research suggests that irinotecan cytotoxicity due to DNA synthesis process. Replicase and a topoisomerase I-DNA irinotecan (or SN-38) triple complex interactions, causing DNA double-strand breaks. Mammalian cells can not efficiently repair the DNA double-strand breaks


Benefits of Irinotecan powder
1.Irinotecan Hydrochloride (CPT-11) is an intravenous antineoplastic agent. Irinotecan Hydrochloride is a potent anticancer drug with activity in a broad range of experimental tumor models. Irinotecan Hydrochloride is one of many water-soluble derivatives of camptothecin (CPT), a cytotoxic plant alkaloid isolated from the Chinese tree Camptotheca acuminate. Irinotecan Hydrochloride has activity in colorectal cancer similar to 5-fluorouracil and appears to be partially non-crossresistant.
2.This product is antineoplastic. It is the first medicine that is used for treating the metastatic colon rectum cancer; it also has very good effects to non- small-cell carcinoma of the lung and small-cell carcinoma of the lung.


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Xi'an Fengzu Biological Technology Co.,Ltd
Manufacturer Add: Industrial Park in Wugong County, Xianyang City,Shaanxi Province, China.
Office Add: 21F, Tangfengguoji,No.18 Fenghuinanlu, Xi'an City, Shaanxi Province, China.
Office Tel: 86-029-89561932/86-135-7248-9476             Office Fax: 86-029-8918-9705
Email: sales@fengzusw.com                                            Skype: fengzusw