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Bulk Supply Best Quality Pyridoxal Phosphate,USP EP Pyridoxal Phosphate

Bulk Supply Best Quality Pyridoxal Phosphate,USP EP Pyridoxal Phosphate

Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic reactions. FZBIOTECH,as a manufacturer of API, has been devoting to supplying the best quality Pyridoxal phosphate to all over the world with best price. For long term cooperation, free sample is available.Chat Now
Description

Basic information of Pyridoxal Phosphate

Product Name: pyridoxal 5'-phosphate

CAS Number: 54-47-7

Molecular Formula: C8H10NO6P

Molecular Weight: 247.14

Appearance:White or light yellow powder

Assay:99%

Structural Formula:

Pyridoxal phosphatE.png

 

Introduction of Pyridoxal phosphate

Pyridoxal phosphate (PLP, pyridoxal 5'-phosphate, P5P), the active form of vitamin B6, is a coenzyme in a variety of enzymatic reactions. The Enzyme commission has catalogued more than 140 PLP-dependent activities, corresponding to ~4% of all classified activities.The versatility of PLP arises from its ability to covalently bind the substrate, and then to act as an electrophilic catalyst, thereby stabilizing different types of carbanionic reaction intermediates.

 

Benefits of Pyridoxal phosphate

PLP acts as a coenzyme in all transamination reactions, and in certain decarboxylation, deamination, and racemization reactions of amino acids.The aldehyde group of PLP forms a Schiff-base linkage (internal aldimine) with the ε-amino group of a specific lysine group of the aminotransferase enzyme. The α-amino group of the amino acid substrate displaces the ε-amino group of the active-site lysine residue in a process known as transaldimination. The resulting external aldimine can lose a proton, carbon dioxide, or an amino acid sidechain to become a quinoid intermediate, which in turn can act as a nucleophile in several reaction pathways. 


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